General Information

  • ID:  hor001040
  • Uniprot ID:  NA
  • Protein name:  FMRFamide-related peptide
  • Gene name:  NA
  • Organism:  Caenorhabditis elegans
  • Family:  FMRFamide related peptide family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  ADDGAPLIRF
  • Length:  10
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Have inhibitory effects on?A. suum?muscle strips,
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor001040_AF2.pdbhor001040_ESM.pdb

Physical Information

Mass: 123493 Formula: C48H75N13O15
Absent amino acids: CEHKMNQSTVWY Common amino acids: AD
pI: 4.11 Basic residues: 1
Polar residues: 1 Hydrophobic residues: 5
Hydrophobicity: 12 Boman Index: -1498
Half-Life: 4.4 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 98
Instability Index: 1128 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  11527423
  • Title:  Isolation and Preliminary Biological Assessment of AADGAPLIRFamide and SVPGVLRFamide from Caenorhabditis elegans